To characterize a drug, medicine or toxic. To know what is the R & D of a drug. Understanding the regulation system in Portugal and Europe. To know very well the ADME system and how drugs act and how drugs are tested. To have notions of Evidence Based Medicine. To understand interactions. To characterize and understand neurotransmission and neuromodulation. To know the pharmacology of pain and pain control. Understanding what are biological medicines, generic drugs and biosimilars. Have notions of pharmacoeconomics.
General concepts. OTC´s and prescription drugs. Self-medication. Generic drugs. Regulation of medicines. Molecular Pharmacology. Evidence Based Medicine. Clinical trials and rational choice of a drug. Pharmacokinetics and pharmacodynamics. Interactions. Adverse reactions and toxic effects. Neurotransmission and neuromodulation. Drugs of the autonomic nervous system. Central and peripheral analgesics. Nonsteroidal antiinflammatory drugs and steroids drugs. Rheumatic disease modifying drugs (DMARD´s). Biological drugs. Local anesthetics. General anesthetics. Pre-anesthetic medication. General inhalation anesthetics, intravenous and intramuscular anesthetics. Recovery room. Miorelaxants. Antihistamines H1 or H2. Pharmacoeconomics.
There are theorical lessons in the classroom, and teaching in groups, performing tasks or solving problems or cases. The student will also develop a workbook, which is part of his portfolio, and shall be assigned topics that have to be developed through research. The student will also do a Personal Medication Formulary, choosing drugs in a way rationally structured.
Assessment:
Midterm exam:85%
Problem solving report:15%
•Rang and Dale´s Pharmacology, Rang et al. edts, Elsevier
•S Guimarães, Daniel Moura e Patrício Soares da Silva Coordenadores. Terapêutica Medicamentosa e Suas Bases Farmacológicas, 5ª ed., 2006 Porto Editora.
•Bertram G. Katzung, Basic & Clinical Pharmacology, Int. Edition, McGraw Hill Companies.
•Goodman & Gilman, The Pharmacological Basis of Therapeutics, McGrawHill Companies.
•deVriesTPGM, TPGM, Henning DH, Hogerzeil HV and FresleD. Guide to Good Prescribing. OMS ,Genève , 1995
•NOTA: antes das aulas teóricas serão fornecidos os slides (pelo nónio)
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